New drug being developed using compound found in red wine 'could help humans live until they are 150'

• Drugs are synthetic versions of resveratrol, found in red wine
• Research shows drugs which could prevent cancer and diabetes now viable
• Medication can be taken topically or orally
• No drugs yet developed to target aging skin

By LUCY CROSSLEY

PUBLISHED: 15:48 EST, 10 March 2013 | UPDATED: 16:40 EST, 10 March 2013

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Breakthrough: The new anti-aging drugs are synthetic versions of resveratrol which is found in red wine

Drugs that could combat ageing and help people to live to 150-years-old may be available within five years, following landmark research.

The new drugs are synthetic versions of resveratrol which is found in red wine and is believed to have an anti-ageing effect as it boosts activity of a protein called SIRT1. 

Pharmaceutical giant GlaxoSmithKline has been testing the medications on patients suffering with medical conditions including cancer, diabetes and heart disease.

The work proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.

As each of the 117 drugs tested work on the single enzyme through a common mechanism is means that a whole new class of anti-ageing drugs is now viable, which could ultimately prevent cancer, Alzheimer's disease and type 2 diabetes.

Genetics professor David Sinclair, based at Harvard University, said: 'Ultimately, these drugs would treat one disease, but unlike drugs of today, they would prevent 20 others.

'In effect, they would slow ageing.'

The target enzyme, SIRT1, is switched on naturally by calorie restriction and exercise, but it can also be enhanced through activators.

The most common naturally-occurring activator is resveratrol, which is found in small quantities in red wine, but synthetic activators with much stronger activity are already being developed.

Although research surrounding resveratrol has been going on for a decade, until now the basic science had been contested.

 

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Despite this, there have already been promising results in some trials with implications for cancer, cardiovascular disease and cardiac failure, type 2 diabetes, Alzheimer's and Parkinson's diseases, fatty liver disease, cataracts, osteoporosis, muscle wasting, sleep disorders and inflammatory diseases such as psoriasis, arthritis and colitis.

Professor Sinclair said: 'In the history of pharmaceuticals, there has never been a drug that tweaks an enzyme to make it run faster.'

Positive: Scientists have been testing the medications on patients suffering with medical conditions including cancer, diabetes and heart disease (file picture)

The technology was sold to GlaxoSmithKline in 2008. 

Four thousand synthetic activators, which are 100 times as potent as a single glass of red wine, have been developed - with the best three being used in human trials.

Writing in the journal Science, Professor Sinclair, who suggests the first therapeutic to be marketed will be for diabetes, said: 'Our drugs can mimic the benefits of diet and exercise, but there is no impact on weight.'

Limited trials have been carried out in people with type 2 diabetes and the skin inflammatory disease, psoriasis. 

Scientists found that there were benefits to the metabolism in the first group and a reduction in skin redness in the second.

The drugs can be administered orally, or topically. 

So far, there have been no drugs developed to target ageing skin, but one major skin care range has developed a creme with resveratrol in it.

Anti-aging: Drugs to target ageing skin have not yet been developed, but one major skin care range has created a creme containing resveratrol

While any drug would be strictly prescribed for certain conditions, Professor Sinclair suggests that one day, they could be taken orally as a preventative.

They could therefore be used in the same way as statin drugs are commonly prescribed to prevent, instead of simply treating, cardiovascular disease.

In animal models, overweight mice given synthetic resveratrol were able to run twice as far as slim mice and they lived 15 per cent longer.

Professor Sinclair added: 'Now we are looking at whether there are benefits for those who are already healthy.

'Things there are also looking promising. We're finding that ageing isn't the irreversible affliction that we thought it was.

'Some of us could live to 150, but we won't get there without more research.'

Read more: http://www.dailymail.co.uk/health/article-2291254/New-drug-developed-using-compound-red-wine-help-humans-live-150.html#ixzz2NC8fNy2n
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U.S. Treasury vs Federal Reserve It Is Getting Ugly

Tom Heneghan explosive intelligence briefings ALL patriot Americans MUST know, with sources inside American/European intelligence agencies and INTERPOL, reporting what is really going on behind the scenes of the corporate-controlled, fascist, extortion-friendly propaganda U.S. media's massive deceptions
Sunday March 10, 2013
U.S. Treasury vs Federal Reserve
It Is Getting Ugly
by Tom Heneghan
International Intelligence Expert



UNITED States of America - It can now be reported that U.S. Treasury Secretary Jack Lew engaged in a major verbal shouting match with Federal Reserve Chairman Bernard Bernanke last Friday evening.

Secretary of the Treasury, Jack Lew (L),
and privately owned Federal Reserve Chairman
traitor Ben Bernanke
EPA/JIM LO SCALZO

As Wanta-Reagan-Mitterrand Protocol implementation remains imminent (a Supreme Court ordered April 1st deadline) Lew accused Bernanke of illegal conversion of funds in his continuing comingling of the Wanta-Reagan-Mitterand Protocols.

Note: Bernanke recently transferred billions of dollars of U.S. Taxpayers' funds to foreign financial institutions with the European Central Bank (ECB) being used as the pimp.

The ECB and its soon to be indicted President Mario Draghi then used the funds to buy euro currency and sell short the Japanese yen orchestrating a foreign currency ponzi scheme that helped boost the prices and valuations of U.S. and European as well as Japanese stock markets.

The ponzi scheme was also used to prop up the hocus pocus euro denominated balance sheets of U.S. banking giants, the gangster banks Goldman Sachs and JPMorgan Chase.

Speaking of JPMorgan and Goldman Sachs, last Friday the U.S. Treasury did a preemptive strike against the criminal privately owned Federal Reserve when they leaked the real stress tests on JPMorgan and Goldman Sachs.

The stress tests proved negative.

The stress tests detailed that the two aforementioned banking gangsters have massive exposure to derivative debt and have record over margined positions using illegal cross-collateralized derivatives on the corrupt London LIFFE exchange utilizing naked options in the rigging of foreign currency, precious metals and stock index future contracts that are traded on worldwide financial markets.

Note: The U.S. Treasury is now in position of 'smoking gun' evidence that proves that JPMorgan and Goldman Sachs current spread sheets are 85% worthless derivatives and only 15% cash.

P.S. STAND WITH RAND

Once again, congratulations to Senator Rand Paul, Republican of Kentucky, for standing up for the U.S. Constitution against the neo-Nazi Obama Soteoro administration and its totally corrupt Attorney General Eric Holder and neo-Nazi lesbian Department of Homeland Security Secretary Janet Napolitano.

Thanks to great American patriot Rand Paul there is good news.

THE U.S. MILITARY IS NOW READY TO PIVOT when it comes to Holder and Napolitano as well as check kiter and money launder Bernard Shalom Bernanke.

Bernanke is now complaining that he is getting anti-semetic threats from U.S. military
personnel.

Message to Bernanke: Quit playing the Jew card. You were warned twice by the U.S. military to stop comingling Wanta-Reagan-Mitterrand Protocol funds and using U.S. Taxpayers' money on behalf of FOREIGN financial institutions and crooked U.S. banks that LOOTED the U.S. Treasury and then got bailed out, otherwise known as financial TREASON!

Clearly, Mr. Bernanke, you do not listen, so maybe you should buy a hearing aid but do it with your own money, NOT U.S. Taxpayers' money.

P.P.S. The crooked bank-controlled, extortion friendly U.S. media is still promoting the Bush-Clinton Crime Family Syndicate control over the United States.

CNN aka CIA news network was busy suggesting a Jeb Bush vs Hillary Clinton possible 2016 election match up.

Note: It is doubtful this country ever makes it to 2016 let alone the end of the month, despite that CNN remains totally sociopathic and on the take.

Repeat after me: It is Bush vs Bitch, bank, bank bank and its Bitch vs Bush, bank, bank, bank.

Message to Jeb Bush: Lets get immigration reform started. The first thing we can do is deport your whole Nazi German 'Skull and Bones' election stealing, nation wrecking family from American soil, destination Paraguay.

Once you all arrive in Paraguay, year 2000 duly elected President Albert Gore Jr. will then place you all in a sinkhole. Now that IS immigration reform, folks!

Remember, folks, the U.S. media is TOTALLY CONTROLLED by the crooked banks, along with the Bush-Clinton-Obama-Geithner-Paulson-Bernanke Crime Family Syndicate that LOOTED the U.S. Treasury and shredded our Constitution.

So, STAND WITH RAND.

Example of media whores:

Extortion friendly David Gregory of NBC Meet the Press was a regular customer at Barney Frank's homosexual and pedophile whore house and has been on the take from the Bushes and Clintons for years.

CO-CONSPIRATORS
MSNBC Chrissy Pooh Matthews embraces
Bush-Clinton Crime Family Syndicate'sHillary Bitch Clinton
source nydailynews. com, mediabistro. com

Then there is Twitty Bird aka Chrissy Pooh Matthews of MSNBC. Chrissy Pooh bragged about voting for George W. BushFRAUD in the year 2000 so as to pave the way for Hillary Bitch and is now enabling a U.S. police state by promoting the FBI Division 5 controlled Southern Poverty Law Center (SPLC) that wants to dismantle the 1st, 2nd, 4th and 5th Amendments to the Constitution of the United States.

The Southern Poverty Law Center believes that anyone who believes in the Constitution of the United States is either a racist or anti-semite.

Message to Chrissy Pooh Matthews: Why don't you go fly a drone, you moron!

Then there are the two moron bookends Erin Burnett and Anderson Cooper of CNN. Burnett recently mocked Senator Rand Paul while both Burnett and Cooper regularly trash the U.S. Constitution, but constantly promote sodomy and sexual deviancy.

There is a rumor out that Cooper and Burnett are going to run an online gay dating service with Wolf Blitzer, George W. BushFRAUD and Hillary Rodenhurst Clinton as co-hosts.

Note: It should also be mentioned that all of these aforementioned cable news network actors and actresses got insider trading tips from former General Electric (GE) CEO Jack Welch and soon to be indicted Steven Cohen of SAC Capital.

P.P.P.S. Congratulations to Leslie Stahl of CBS news for her excellent 60 Minutes piece on Chinese ghost cities and the collapsing Chinese economy.

CBS is the only network with real journalists who are not actors, actresses and bimbos.

Bill Plante, Bob Shieffer and Leslie Stahl make half the salary than these aforementioned cable news network morons and propagandists.

Just turn off the cable news network shows and click on to the CBS website, some real big news is coming from CBS.

As you look for the truth, look to CBS News.

In closing, speaking of China word is out China will devalue the Chinese yuan at 6:00 p.m. eastern standard time.

This action is directly aimed at the Central Bank of Japan, which is currently financing a Black Op involving North Korea and alleged nuclear threat versus the U.S. and Japan.

Question: Who is really making these threats from North Korea?

Could it be Dennis Rodman who is using his cell phone in the lobby of the Federal Reserve Bank of New York.

Related:
[copy and paste url links below, be sure to remove the space between . (and) com]

Fed Injects Record $100 Billion Cash Into Foreign Banks Operating In The US In Past Week
http://www.blacklistednews. com/Fed_Injects_Record_$100_Billion_Cash_Into_Foreign_Banks_Operating_In_The_US_In_Past_Week/24653/0/38/38/Y/M.html

China's Economy Off to Weakest Start Since 2009
http://www.zerohedge. com/news/2013-03-09/chinas-economy-weakest-start-2009

Rand Paul and the 13-Hour Filibuster by Drake

New post on Americannationalmilitia.com

Rand Paul and the 13-Hour Filibuster by Drake I suggest those who are interested to join. I did. ~Drake Rand Paul Filibusters Brennan for 13 Hours by Sondra Clark On Wednesday, Senator Rand Paul literally stood on his principles. Paul led a 12 hour and 54 minute filibuster, delaying confirmation of John Brennan as Director of the CIA. Brennan is a marginally-qualified candidate with a history of promoting what The Heritage Foundation’s Steven Bucci calls “the overuse of drones.” “I will speak until I can no longer speak,” Paul began. “I will speak as long as it takes, until the alarm is sounded from coast to coast that our Constitution is important.” This was the ninth-longest speech in the Senate’s history. Paul filled the nearly 13 hours by speaking out against drone strikes and especially the administration’s recent claims that it could use drones domestically. Bucci says Paul was right to critique the domestic use of drones: As Heritage has stated before, use of armed drones inside the U.S. would be foolish and wrong. The Administration’s assertion is a dangerous overreach. In general, the overuse of drones as the counterterrorism method of choice has turned into Obama’s equivalent of Bill Clinton’s use of cruise missiles. Both appear to be cheap and easy. Unfortunately, when used at the exclusion of other military and intelligence means, all you get is press coverage, but not lasting results. The President must utilize a comprehensive counterterrorism policy that uses all the tools available. Paul was not alone in his filibuster. He was joined by Sens. Ron Wyden (D-OR) and rising conservative stars Mike Lee (R-UT), Ted Cruz (R-TX), Pat Toomney (R-PA) and Marco Rubio (R-FL). Video: Toomey explains why he joined Paul's filibuster. When Paul was finished he received an unprecedented round of applause for his effort. The applause drowned out the Chair’s pronouncement that “No signs of approval or disapproval are permitted on the Senate floor." Paul’s efforts were not in vain. Attorney General Eric Holder sent him a letter today affirming that the president lacks the authority to use drones to attack noncombatant U.S. citizens on American soil. What do you think of Rand Paul’s filibuster? Why States Should Resist Obamacare Many state governments continue to resist setting up the health insurance “exchanges”—now rebranded as “marketplaces”—that form a core part of Obamacare. “Right now, it’s more practical for states to hold off on the exchange mania,” Heritage Foundation health care scholar Ed Haislmaier writes in the Hill. For one thing, these exchanges impose huge new costs on states, and the alternative, letting the federal government run the exchanges, is far less costly. He continues: Recognizing the inherent risk and faulty foundation of ObamaCare’s exchanges is the first important step for states. The next is rejecting the proposed Medicaid expansion. There will be many who argue a Medicaid expansion, like an ObamaCare exchange, is a good idea. But the promises of no cost, more control and helping low-income Americans fall flat. Like the exchange, the Medicaid expansion threatens to usher in long-term costs, zero flexibility for the existing program and greater dependence on government-run healthcare. Heritage recently sent lawmakers a plan, America’s Opportunity for All, that explains how to get America back on track. It urges Congress to repeal Obamacare and create a patient-centered system based on free enterprise. Do you think the states will be able to hold off Obamacare? With Hugo Chávez Gone, What's Next for Venezuela? The death this week of Venezuelan despot Hugo Chávez death this week, while not a surprise given his health, is still a big deal. “Chávez’s death has far-reaching—and potentially dangerous—implications for the U.S. and the world, “ The Heritage Foundation’s Jessica Zuckerman explains. Recent actions by interim president Nicolás Maduro “threaten to take a dangerous situation from bad to worse,” Zuckerman says, and could “spark strong anti-American violence in Venezuela like that seen throughout the Middle East late last year.” Maduro went so far as to blame the United States for Chávez’s illness. While plainly ridiculous, in Venezuela these remarks may be taken seriously.  This might be the first big problem Secretary of State John Kerry has to deal with, especially since Venezuela has ties to Iran and terrorist groups like Hezbollah. Read more on myHeritage.org Drake | March 10, 2013 at 8:59 am | Categories: News | URL: http://wp.me/p2tRr3-JY

So God made a Dog ...

So God made a Dog ...

Subject: Fwd: So God made a Dog ...
Date: Sun, 10 Mar 2013 16:43:14 -0400

                         So God made a Dog ...

For all of you people who know how much a dog can add to your life.....

http://www.youtube.com/watch?v=lJ7AfSO2fKs