Nanoparticles
Loaded with Bee Venom Kill HIV
By Julia
Evangelou Strait
news.wustl.edu
March 9, 2013
news.wustl.eduMarch 9, 2013
Nanoparticles carrying a toxin found in bee venom can
destroy human immunodeficiency virus (HIV) while leaving surrounding cells
unharmed, researchers atWashington University School of Medicine in St. Louis have
shown. The finding is an important step toward developing a vaginal gel that
may prevent the spread of HIV, the virus that causes AIDS.
“Our hope is that in
places where HIV is running rampant, people could use this gel as a preventive
measure to stop the initial infection,” says Joshua L. Hood, MD, PhD, a
research instructor in medicine.The study appears in the current issue of Antiviral Therapy. (photo-JOSHUA L. HOOD, MD, PHD. Nanoparticles (purple) carrying melittin (green) fuse with HIV (small circles with spiked outer ring), destroying the virus’s protective envelope. Molecular bumpers (small red ovals) prevent the nanoparticles from harming the body’s normal cells, which are much larger in size.)
Bee venom contains a potent toxin called melittin that can poke holes in the protective envelope that surrounds HIV, and other viruses. Large amounts of free melittin can cause a lot of damage. Indeed, in addition to anti-viral therapy, the paper’s senior author, Samuel A. Wickline, MD, the J. RussellHornsby Professor of Biomedical Sciences, has shown melittin-loaded nanoparticles to be effective in killing tumor cells.
3 comments:
Sounds great for tumors! But, "it's always best to isolate the virus, BEFORE recommending treatment". And HIV, has yet to even be isolated, in over 30 y-e-a-r-s;
http://www.omsj.org/innocence-group
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